Author: creativebiomart

The Tumor Necrosis Factor (TNF) Superfamily of proteins represents one of the most biologically influential groups of cytokines in immunology and cell biology. Characterized by their shared structural motifs and receptor-interacting domains, these proteins orchestrate a wide spectrum of cellular processes—ranging from immune cell activation and survival to programmed cell death. Their profound impact on homeostasis and disease underscores their central importance in both basic research and clinical intervention. A Complex Network of Ligand-Receptor Interactions The TNF superfamily encompasses at least 19 ligands and nearly 30 cognate receptors. Most ligands exist as type II transmembrane proteins, although several also have…