To appreciate the flavor, you have to understand the hardware. The MO5000 uses a draw-activated firing mechanism, meaning there are no buttons to press.
When looking at geek bar flavors ranked by the community, the general consensus is that the fruit flavors (like Mexico Mango) perform best on regular settings, while the “Ice” and “Sour” editions (like Sour Mango Pineapple) shine when the device is boosted.